What time of day should intake vitamin B12? (2023)

The best time to take your daily dosage of vitamin B12 is in the morning. It’s important to take your vitamin B12 at the same time each day to ensure that your body benefits from a steady stream of the vitamin throughout the day.

This is especially important because vitamin B12 is a water-soluble vitamin and is not stored in the body. Any intake of vitamin B12 that is not used right away is eliminated in the body. If you take your vitamin B12 in the morning, you can make sure that it’s being properly used rather than flushed out of the body.

It’s best to take your vitamin B12 with a meal so that your body can use it immediately.


  • What is the right time to take vitamin B12?
  • Should vitamin B12 be taken with food?
  • Should you take B12 with food or on an empty stomach?
  • What happens if you take B12 in the evening?
  • Can you take B12 and vitamin D together?
  • What medications should not be taken with B12?
  • Can I take B12 with coffee?
  • When should I take B12 morning or night?
  • Is it OK to take 1000 mcg of B12 a day?
  • Can you take B12 complex at night?
  • Does B12 make you sleepy?
  • Why You Should Take B12 at night?
  • Is it OK to take B12 before bed?

What is the right time to take vitamin B12?

The best time to take vitamin B12 is usually in the morning, since supplements can interfere with your sleep. It’s best to take supplements with food and spread them throughout the day, as B12 is better absorbed when paired with other nutrients.

Taking other medications or herbal supplements can also affect how you absorb B12, so it is best to talk to your doctor about timing and optimal doses. That said, B12 is a water-soluble vitamin, which means it’s easily and quickly absorbed, so taking it at different times of the day doesn’t make much difference in terms of absorption.

Ultimately, when you take your vitamin B12 is up to you, as long as you are taking it consistently and at the recommended dosage.

Should vitamin B12 be taken with food?

Yes, vitamin B12 should be taken with food, as it is a water-soluble vitamin, meaning it cannot be stored in your body and must be replenished daily. Without food, your body cannot absorb the vitamin, meaning taking it on an empty stomach will not benefit you in any way.

(Video) When to take VITAMIN B12 (Best Times/Tips) 2021

Additionally, vitamin B12 is also found in a number of food sources such as eggs, meat, and fish, so having it with meals can help ensure you are getting enough to meet your daily needs. Taking vitamin B12 alongside meals also helps to ensure adequate levels of the vitamin in your body.

Finally, the absorption of vitamin B12 can be improved with the help of other B vitamins, so by taking the vitamin in combination with other B vitamins found in food, you can help ensure maximum absorption.

Should you take B12 with food or on an empty stomach?

It is likely safe to take B12 vitamin supplements with or without food. However, taking it with food may help improve absorption, particularly if you have difficulty absorbing B12, such as in pernicious anemia.

Vitamin B12 is a water-soluble vitamin, meaning that it is not stored in your body, but rather absorbed and used immediately. Therefore, it is a good idea to try to get as much as you can from your food and supplement with a B12 supplement.

Taking B12 with food may help to increase absorption, although it is not clear by how much. Taking B12 supplements on an empty stomach also likely helps improve absorption. However, if you have difficulty absorbing B12 due to a condition like pernicious anemia, you may find that taking it with food helps you to benefit more from the vitamin.

Additionally, taking B12 at the same time as eating foods high in iron or calcium, such as milk and iron-fortified cereals, may interfere with absorption. Lastly, B12 absorption can also be affected by certain medications, notably proton pump inhibitors, so if you are taking these medications you should talk to your doctor about the best way to take B12.

What happens if you take B12 in the evening?

Taking B12 in the evening can be beneficial, as B12 is an important nutrient that can help improve energy levels and mood. Studies have shown that B12 is best absorbed when taken on an empty stomach, so taking it in the evening may be ideal as the body is primed to receive the vitamin.

However, it is important to remember that B12 is stored in the body and any excess taken can be excreted, so it is not necessary to take it daily unless you are deficient in the vitamin. Additionally, it may be beneficial to take B12 with other vitamins and minerals such as folic acid or iron, to enhance absorption and ensure that it is properly utilized by the body.

Ultimately, it is up to the individual if they choose to take B12 in the evening, however it is important to consult with a health care professional to ensure that the B12 is being taken in the way that best meets the individual’s needs.

(Video) The Optimal Vitamin B12 Dosage for Adults

Can you take B12 and vitamin D together?

Yes, you can take B12 and vitamin D together. Both are important vitamins that can be beneficial when taken together. Vitamin B12 plays an important role in creating red blood cells and DNA and helps keep our nerve and blood cells healthy.

Vitamin D helps the body absorb calcium, which is needed to form bones and teeth. Taking them together can provide support for our overall health as well as help to prevent some conditions such as anemia.

It’s important to take the right dosage for each vitamin, as taking too much can bring about a variety of side effects. Before taking them together, it is best to consult with your doctor or healthcare provider to ensure that it is safe for you and to review the specific dosages.

What medications should not be taken with B12?

Certain medications should not be taken with vitamin B12. These medications include metformin, chloramphenicol, colchicine, cholestyramine, and colestipol. Metformin is used to treat type 2 diabetes and chloramphenicol is an antibiotic.

Colchicine is used to treat gout and cholestyramine and colestipol are both used to reduce cholesterol by binding to bile acids in the intestine. Taking any of these medications with vitamin B12 can interfere with its absorption in the body, so they should not be taken together.

Additionally, some other medications may also interact with B12, such as proton pump inhibitors, antacids, or drugs containing aluminum or calcium. You should discuss your current medication use with your healthcare provider before taking vitamin B12 supplements to avoid any potential interactions.

Can I take B12 with coffee?

Yes, you can take B12 with coffee. B12 is a water-soluble vitamin, so it can be taken with coffee without any negative effects. However, since caffeine can affect absorption, it is best to wait at least an hour after taking B12 before consuming coffee.

In addition, too much caffeine can cause uncomfortable side effects like upset stomach, headaches, or excess energy. Therefore, it is important to moderate your caffeine intake, and to always check with a healthcare professional if you have any questions or concerns.

When should I take B12 morning or night?

(Video) When to Take Vitamins and Supplements ? – Dr.Berg

The best time to take B12 depends on the form of the supplement that you are using and your body’s absorption rate. If you are taking a B12 supplement orally, it is best to take it in the morning. This is because B12 is a water-soluble vitamin, which means your body does not store it for long periods of time and it should be taken regularly for the best absorption.

Natural sources of B12 such as meat, eggs, and dairy are best consumed at any time of the day, since they do not require to be taken with food as supplements do. However, if you are taking a sublingual B12 supplement, it is best taken at night before bed.

This is because they dissolve under your tongue and do not require food in order to be absorbed. Therefore, it is best to take a sublingual B12 at night when the rest of your digestive system is not as active so that it can be properly absorbed.

Is it OK to take 1000 mcg of B12 a day?

It is not recommended to take more than the recommended dietary allowance for vitamin B12, which is 2. 4 mcg a day for adults. Taking 1000 mcg of vitamin B12 a day could potentially cause adverse side effects.

Vitamin B12 is a water-soluble vitamin, so taking too much of it can cause your body to accumulate too much of it in the bloodstream. This could lead to an imbalance of your vitamin B12 levels, which can cause symptoms such as headaches, brain fog, fatigue, dizziness, heart palpitations, mood swings, and stomach upset.

Additionally, taking too much B12 can interfere with how medications work, so it is important to be mindful of the medication you are taking and make sure to check in with your doctor first before taking any large doses of vitamin B12.

Can you take B12 complex at night?

Yes, it is safe to take B12 complex at night. B12 is a water-soluble vitamin, meaning the body doesn’t store it and it needs to be replenished through diet or supplementation. It is best to take a B12 complex along with other water-soluble vitamins like B1, B6, and B-complex vitamins in the evening.

This ensures that the body can receive the necessary amount of B12 and other nutrients throughout the night and early morning. Additionally, B12 complex helps support restful sleep and can help reduce occasional mild stress or nervousness.

(Video) VITAMIN B12 dosing strategies – 3 examples (and what I recommend)

However, it is best to talk to a medical professional before starting a dietary supplement.

Does B12 make you sleepy?

No, there is no scientific evidence to suggest that B12 will make you sleepy. B12 is an essential vitamin that is important for the body to function properly. Specifically, B12 helps to support a healthy nervous system and helps to produce red blood cells.

While a lack of B12 can cause symptoms such as fatigue and drowsiness, having an adequate amount of B12 is not likely to make you sleepy. It is possible that having more B12 than is necessary could make you feel sleepy in some cases, but only when taken in very large doses.

Additionally, while B12 is often included in multivitamins and many energy drinks, there is no evidence to suggest it has any effect on alertness or energy levels. Ultimately, B12 is an important nutrient for overall health, but there is no evidence to suggest it will make you sleepy.

Why You Should Take B12 at night?

Taking B12 at night is beneficial because it helps with energy production and cognitive function. B12 is important for energy production and helps to create energy in the form of ATP or “Adenosine Triphosphate.

” B12 helps the body to process proteins, proteins are the building blocks of cells and tissues. B12 helps to prevent fatigue and anemia and can help improve mental clarity and focus which can be beneficial when studying late at night.

B12 also helps to promote healthy sleep, which is especially important during exam season. B12 works with the body’s 24-hour circadian rhythm, which is disrupted if a person doesn’t have enough B12. Taking B12 at night helps the body to experience a balanced level of B12 to ensure healthy sleep and energy production during the day.

Additionally, B12 helps to regulate levels of the “sleep hormone” melatonin, which is important for deep and restful sleep. By taking B12 at night, you are helping the body to balance this hormone which can enable healthier and more restful sleep.

Is it OK to take B12 before bed?

Yes, it is generally safe to take B12 before bed. Generally, B12 is well-tolerated, so there should be no major adverse side effects. In addition, B12 has several potential benefits, including increased energy, improved sleep, and a reduction in stress and anxiety, that may make it beneficial to take before sleeping.

(Video) Is Too Much B12 Bad (Can You Take Too Much b12?)

However, it is important to speak to your healthcare provider before taking any supplements to ensure they are right for you. Depending on your individual health needs, they may recommend a different dose, schedule, or type of B12 supplement.


How much vitamin B12 should you take in a day's time? ›

While the recommended daily amount of vitamin B-12 for adults is 2.4 micrograms, higher doses have been found to be safe. Your body absorbs only as much as it needs, and any excess passes through your urine. High doses of vitamin B-12, such as those used to treat a deficiency, might cause: Headache.

Is it OK to take vitamin B12 before bed? ›

You can definitely opt for taking vitamin B12 supplements at night if that's what works best for you, although the natural energy-boosting abilities of vitamin B12 might be put to better use as you're starting the day.

Is it OK to take 1000 mcg of B12 a day? ›

But if you need more vitamin B12 than what your diet provides, that's when supplements can come in. If you are low in vitamin B12, a common recommended dose for oral supplements is about 1,000 mcg daily.

Should vitamin B12 be taken with food or on an empty stomach? ›

For example, it's recommended that people with a B12 deficiency take B12 supplements on an empty stomach with water to promote maximal absorption (12).

What is the best B12 supplement for seniors? ›

Other B12 Options for Seniors
  • Nature Made Vitamin B12 Gummies. ...
  • Thorne Research Methylcobalamin. ...
  • Pure Encapsulations B12 with Folate. ...
  • Natrol Vitamin B12 Fast Dissolve Tablets. ...
  • Triquetra Organic Vitamin B12. ...
  • Solimo Vitamin B12 3,000 mcg. ...
  • Nutricost Vitamin B12. ...
  • Mt Angel Vegan Vitamin B12 Sublingual Drops.
Oct 11, 2022

Is 2000 mg of B12 too much to take daily? ›

Though doses of up to 2,000 mcg of vitamin B12 are considered safe, it's best to speak with a doctor to find out whether taking a supplement is necessary. Most people can fulfill their B12 needs through a nutrient-rich diet.

Can I take vitamin D and B12 together? ›

Fat-soluble and water-soluble vitamins

For example, although it's safe to take vitamin D with vitamin B12, it's not advisable, says Virgilio Sanchez, MD, a board certified family medicine physician at Conviva Care Center in Miami, Florida.

What are the symptoms of low B12? ›

Symptoms of vitamin B12 deficiency
  • a pale yellow tinge to your skin.
  • a sore and red tongue (glossitis)
  • mouth ulcers.
  • pins and needles (paraesthesia)
  • changes in the way that you walk and move around.
  • disturbed vision.
  • irritability.
  • depression.

Can I take vitamin D and B12 at night? ›

As a general rule of thumb, take your B vitamins in the morning or with a meal. Vitamin B12, for example, should definitely be taken in the morning. This is because it is important for energy metabolism, which may interrupt your sleep if taken at night.

What medications should not be taken with B12? ›

As summarized in the table provided, vitamin B12 (cobalamin) absorption and utilization by the body can be compromised with the chronic use of certain medications which include: colchicine, chloramphenicol, ethanol, histamine 2 receptor antagonists (H2RA), metformin, and proton pump inhibitors (PPI).

Is taking B12 everyday good for you? ›

For most adults, the recommended dietary allowance (RDA) is 2.4 micrograms (mcg), though it's higher for people who are pregnant or breastfeeding ( 1 ). Vitamin B12 may benefit your body in impressive ways, such as by boosting your energy, improving your memory, and helping prevent heart disease.

Is a B12 shot better than a pill? ›

B12 injections are absorbed much better by the body because they are administered intramuscularly (into the muscle), and therefore directly into the blood. B12 tablets must pass through the digestive system, which leads to much poorer absorption rates.

Can you take B12 and drink coffee? ›

Furthermore, caffeine interferes with the metabolism of certain B vitamins, including thiamine. However, because caffeine increases stomach acid secretion, it actually boosts the absorption of vitamin B12.

How long should I wait to eat after taking B12? ›

It's usually best to take the tablets on an empty stomach. This means at least 2 hours after a meal or snack and at least 30 minutes before you eat again.

What happens if you take B12 without food? ›

Vitamin B-12

Some B vitamins are poorly absorbed, with or without food, and B-12 is a good example. Vitamin B-12 is a large molecule that needs a compound called intrinsic factor to be absorbed in the stomach. Even under ideal circumstances, a very small percentage of dietary or supplemental B-12 is absorbed.

What is the safest form of B12 to take? ›

Cyanocobalamin B12 contains a cyanide molecule that gives it stability in products and the body. Cyanide is a poison, of course, but in the minuscule quantities found in Cyanocobalamin, this is of no consequence – it's perfectly safe to take!

What is the healthiest form of B12? ›

For prevention and treatment of vitamin B12 deficiency, cyanocobalamin in chewable, sublingual, or liquid forms (rather than in a multivitamin) is best under most circumstances.

How much B12 is too much for seniors? ›

Since this nutrient is water-soluble, you don't have to worry about taking too much vitamin B12. The percentage of vitamin B12 that your body can absorb from supplements isn't very high. On average, it's estimated that your body only absorbs about 10mc of a 500 mcg B12 supplement.

Which fruit is rich in vitamin B12? ›

Bananas are a cheap, healthy, and nutrient-dense fruit that can easily become a part of every individual's diet. It is one of the best fruits rich in vitamin B12. Bananas also contain fibre and potassium. It helps manage blood pressure, reduce stress, and relieve constipation and ulcer problems.

What happens if you take 1000 mg of B12? ›

A high-dose B complex supplement (with 1,000 mcg of B-12) hurt, rather than helped, people with type 1 or type 2 diabetes and advanced kidney disease, resulting in a worsening of kidney function and an increase in the risk of heart attack, stroke and death.

When should I take B12 and d3? ›

“Take water-soluble vitamins on an empty stomach with a glass of water,” recommends Dr. Perez-Gallardo. And since it can be energizing, Dr. Perez-Gallardo says that the best time to take vitamin B12 is in the morning, so it won't affect your sleep.

Why should you not take vitamin C and B12 together? ›

Vitamin C and B12

According to Dr. Airey, some studies have shown that Vitamin C could break down Vitamin B12 in your digestive tract, reducing your B12 absorption. As a result, he says you want to wait at least two hours before taking Vitamin C with your Vitamin B12.

What vitamins you shouldn't take together? ›

Don't use calcium, zinc, or magnesium supplements at the same time. Also, these three minerals are easier on your tummy when you take them with food, so if your doctor recommends them, have them at different meals or snacks.

What is the main cause of low B12? ›

Diet. Some people can develop a vitamin B12 deficiency as a result of not getting enough vitamin B12 from their diet. A diet that includes meat, fish and dairy products usually provides enough vitamin B12, but people who do not regularly eat these foods can become deficient.

What depletes B12? ›

Lack of vitamin B12 in your diet: People who don't eat enough foods that naturally have vitamin B12 or don't eat foods fortified with vitamin B12 can develop vitamin B12 deficiency. Gastritis: Gastritis is inflammation of the stomach lining, and it's a common cause of vitamin B12 deficiency.

What causes B12 to go low? ›

Low levels of vitamin B-12 can be caused by: Diet. Vitamin B-12 is mainly found in meat, eggs and milk, so people who don't eat these types of foods may need to take B-12 supplements. Some foods have been fortified with B-12, including some breakfast cereals and some nutritional yeast products.

Does vitamin B12 affect your sleep? ›

B12 also plays a role in the production of melatonin, a hormone that helps regulate our circadian rhythms. It is possible that a deficiency of B12 could lead to disrupted sleep patterns. Vitamin B12 also helps in the production of energy.

Does vitamin B12 give you energy? ›

So does vitamin B12 give you energy? While B12 doesn't directly provide energy, it does give the body the tools it needs to convert food molecules into energy. Getting the recommended daily amount of B12 can therefore help ensure that the body is able to make the energy it needs to do everything you need it to do.

What vitamins are best taken at night? ›

4 Vitamins That Help You Sleep
  • Magnesium. Magnesium is perhaps the most important vitamin or mineral when it comes to sleep. ...
  • Calcium. Calcium has been shown to play a significant role in our sleep cycles, particularly the REM stage of sleep. ...
  • Potassium. ...
  • B Vitamins.
Feb 25, 2022

Does B12 supplement raise blood pressure? ›

The lowering effects of vitamin B12 together with folic acid on blood pressure have been reported in intervention study in adults. However, no study has reported the association of vitamin B12 by itself with systolic or diastolic blood pressure in children or in adults.

What does vitamin B12 do for hair? ›

However, vitamin B12 may give you the appearance of fuller and thicker hair because the increase in oxygen to hair follicles can help stimulate the replacement of lost strands. Vitamin B12 may also help give your hair an overall healthier appearance since intake of enough B12 is responsible for stronger hair shafts.

How can I absorb B12 better? ›

Maintain gut health

Boosting cobalt supplies and fortified meals is essential, but so is increasing absorption power. This is where gut health comes into play since it is important for proper vitamin and nutrient absorption. Vitamin B12 gets absorbed in the stomach, thanks to a protein known as intrinsic factor.

How long after coffee can I take B12? ›

Try to avoid taking your vitamins with coffee or tea

Caffeine also increases urination, which can decrease the concentration of water-soluble vitamins (B-complex and C). So, wait an hour after your morning brew to take supplements.

Does vitamin B12 have to be refrigerated? ›

Vitamin B-12 is stable at room temperature. It doesn't need to be refrigerated.

How long after taking vitamin B12 can I drink coffee? ›

Some beverages, including coffee, contain substances that could interfere with the absorption of some of the nutrients in your vitamin. It's better to drink your coffee about 15 minutes before or a few hours after you take your vitamin.

How long does it take for B12 vitamins to start working? ›

Once you begin treating your vitamin B12 deficiency, it can take up to six to 12 months to fully recover. It is also common to not experience any improvement during the first few months of treatment.

How much B12 is too much? ›

Since B12 is a water-soluble vitamin, it's generally considered safe, even at high doses. No Tolerable Upper Intake Level (UL) has been established for B12, due to its low level of toxicity.

Is it better to take vitamin D in the morning or at night? ›

There's no set time of day that's best to take vitamin D supplements. Some people say taking vitamin D supplements at night is an insomnia risk. There's no research to confirm this, but you might want to take your supplement earlier in the day if you think it's screwing with your sleep.

Is it best to take vitamin D in the morning or at night? ›

While the best timing has not been established, scientific data to confirm anecdotal reports that supplementing at night may interfere with sleep is unavailable. Current research suggests you can fit vitamin D into your routine whenever you prefer.

How long before bed should I take B12? ›

Taking Vitamin B-12 Before Bed

There is no specific time of day recommended when you should take vitamin B-12 supplements, as there is no clinical evidence demonstrating a significant difference between taking vitamin B-12 in the morning or at night.

Will taking B12 at night affect my sleep? ›

Due to its special role, vitamin B12 aids in the prevention of anemia, which mostly leads to fatigue. Even though the research available about the relationship between vitamin B12 and insomnia remains unclear, some studies² show that elevated levels of vitamin B12 do cause sleeplessness.

What happens if you take vitamin B before bed? ›

B vitamins before bed can be very activating to the brain and nervous system, and can make it very hard for you to fall asleep, or stay asleep. For that reason I suggest you take your B vitamins in the morning with breakfast."

Is it better to take vitamin B12 in the morning or night? ›

And since it can be energizing, Dr. Perez-Gallardo says that the best time to take vitamin B12 is in the morning, so it won't affect your sleep.

What is the best form of B12 to take? ›

Methylcobalamin. Methylcobalamin is the most bio-available type of Vitamin B12 which means the body absorbs it more easily. Naturally occurring, it is found in animal-based foods such as meat, fish, milk and eggs so Methylcobalamin B12 is readily available in many people's daily diets.

What is the best way to take B12 vitamin? ›

Comparing the sublingual method to vitamin B12 injections, research found that taking B12 under the tongue had a higher absorption rate, making it a better option (Bensky, 2019). Taking vitamin B12 sublingually may also be a good option for people with a condition called pernicious anemia.

Does B12 give you energy or make you sleepy? ›

Vitamin B-12 has a big role in stabilizing your energy levels. It actually helps give you more energy, rather than making you tired. If you do notice feeling a little fatigued, even though you're regularly taking a B-12 supplement, it's likely a sign of something else that is out of the norm in your body.

What causes B12 deficiency? ›

Some people can develop a vitamin B12 deficiency as a result of not getting enough vitamin B12 from their diet. A diet that includes meat, fish and dairy products usually provides enough vitamin B12, but people who do not regularly eat these foods can become deficient.

Does vitamin B12 help with sleep? ›

It has been found that the vitamin works directly on the brain to help induce sleep. Vitamin B12 benefits have been demonstrated to help patients with sleep disorders, such as insomnia, who have difficulty falling asleep. It has also been shown to improve sleep in healthy individuals depending on the dose that is used.

Can B12 cause insomnia? ›

The direct relationship between insomnia and vitamin B12 levels is yet to be established. However, vitamin B12 deficiency is known to be involved in the pathophysiology of depression, which can commonly be associated with insomnia [19].

When should I take vitamin D morning or night? ›

We recommend taking it with a source of quality fat in the morning or when you break your fast. Avoid taking vitamin D in the evening (we'll talk about why below). Since vitamin D is a fat-soluble vitamin—meaning it doesn't dissolve in water—your body can most easily absorb it when you take it with food.


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